HPA Letter To NHS Staff On Coronavirus

 

 SARS coronavirus – Credit CDC PHIL

 

 

# 6584

 

Although it actually went out to GPs yesterday (Sept 25th), the HPA has today published the letter they sent to NHS staff in England and Scotland on the coronavirus case being treated at a London hospital.

 

This letter provides us with perhaps the most detailed account to date on the events surrounding this case, including contact tracing.

 

 

Patient receiving treatment for novel coronavirus

26 September, 2012

The Department of Health has issued an alert to advise of a case of a novel coronavirus in a patient receiving treatment in a London hospital.

 

On 22 September 2012 a novel coronavirus was identified in lower respiratory tract specimens of a previously well, adult male Qatari national receiving treatment for a severe respiratory illness in London.

Please see the full alert from the Department of Health

 

Publication title: Novel coronavirus in a Qatari national receiving treatment for a severe respiratory illness in London

Document type: Letter

Publication description: This is to advise of a case of a novel coronavirus in a patient receiving treatment in a London hospital.

Publication author: Department of Health

Copyright holder: Crown

DH Gateway number: 18180

Date of publication: 26 September, 2012

Series number: CEM/CMO/2012/15

Some excerpts from the letter (slightly reformatted for readability) include:

NOVEL CORONAVIRUS IN A QATARI NATIONAL RECEIVING TREATMENT FOR A SEVERE RESPIRATORY ILLNESS IN LONDON

On 22 September 2012 a novel coronavirus was identified in lower respiratory tract specimens of a previously well, adult male Qatari national receiving treatment for a severe respiratory illness in London. The virus is virtually identical genetically to a novel coronavirus recently identified by Dutch researchers in a clinical sample from a Saudi Arabian national who was ill with pneumonia over three months ago. These are currently the only two known cases from whom this virus has been isolated.

 

Coronaviruses are causes of the common cold but also include the virus responsible for SARS.  Strict respiratory isolation has been instituted around the current case and all personnel caring for the patient are wearing the appropriate personal protective clothing.

 

Respiratory symptoms in the current case started in early September after a reported visit to Saudi Arabia. The patient was admitted to hospital in Qatar and, as symptoms worsened, was transferred to London by air ambulance on 11 September where he is now being treated in intensive care.

 

Initial routine investigations revealed no cause for the illness but on 21 September, following a report in ProMED describing the identification of a novel human coronavirus, in a fatal respiratory illness in an adult Saudi Arabian national, specimens from the London patient were examined for coronavirus infection, and were found to be positive.Genetic characterisation of the virus revealed that it was virtually identical to the virus that caused the illness in the earlier case from Saudi Arabia.

 

In the light of the severity of the illness in the two confirmed cases and the novel nature of the virus, contacts of the cases, predominantly health care workers, are being contacted to ensure they are well and that further transmission has not occurred. 

 

Follow up of the contacts of the current case is underway; no illness due to this infection has been confirmed so far in this group. Many of these contacts are already likely to be beyond the incubation period (currently assumed to be seven
days, based on what is known about other human coronavirus infections) when symptoms would have developed had they been infected. No other cases of confirmed or probable infection with this virus.

 

Information about these cases, and advice on the need to be vigilant for the possibility of further cases, has been developed for health care workers in the UK. 

http://www.hpa.org.uk/Topics/InfectiousDiseases/InfectionsAZ/RespiratoryViruses/NovelCoronavirus/respinfoforprofnovelcoronavirussept2012/  

 

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Updating Edinburgh’s Legionnaires Outbreak

 

 

# 6372

 

 

Since yesterday, an additional 10 cases of Legionella have been identified in Edinburgh, Scotland bring the total to 61 in a week. It is considered likely that more people are affected, albeit mildly and are not seeking medical care.

 

While no environmental source has been identified, HVAC cooling towers (the most common point of origin) in the south western part of the city have been treated, and it is hoped that this will result in a drop in cases.

 

For more on the origins of this outbreak, and a brief history of Legionnaires diseases, you may wish to revisit (The Legionella Outbreak in South West Edinburgh).

 

You’ll also find a very instructive PDF file available from the ECDC website called:

 

Legionella Pneumonia Geographic Information System: a helpful tool in cluster detection

 

This presentation was made by Sjoerd M. Euser, PhD at the 2010 European Scientific Conference on Applied Infectious Disease Epidemiology (ESCAIDE) in Lisbon in 2010.

 

 

We’ve the latest statement from NHS Lothian, the public health authority in charge of the Edinburgh area.

 

 

Outbreak of Legionella in South West Edinburgh

Update - 07/06/2012 17:30

Legionnaires’ outbreak update - number of cases stands at 61

 

The latest reports from the Scottish Government Resilience Room (SGoRR) on the Edinburgh Legionnaires’ disease outbreak show that there are now 24 confirmed cases and 37 suspected cases.

 

As at 12pm today, of those cases being treated in hospital, 12 were in intensive care and 28 are on general wards.

 

A total of 13 cases are being treated in the community, five have been discharged from hospital and one person has sadly died.

 

Two cases are being treated outwith the NHS Lothian area – one in Highland and one in the north of England. Both of these cases are being treated as part of the south west Edinburgh outbreak and have connections to the area.

 

People that are being admitted to hospital with symptoms are now generally speaking in a better state of health than has previously been the case. The ages of those affected now ranges between 19 and 88, with more males than females affected.

 

As of yesterday, NHS 24 had received 48 calls to the dedicated helpline. However, there was a 20 per cent increase in the number of calls to their regular number about Legionnaire’s disease.

 

The investigation into the source of the outbreak is continuing, with all 16 cooling towers in the affected area now having been inspected.

 

Those cooling towers which were considered to possibly require re-treating are now undergoing this process.

 

Health Secretary Nicola Sturgeon said: “It is a positive sign that those people being admitted to hospital are, generally speaking, less ill than had been the case at the start of the outbreak and we are seeing an increase in the numbers of people well enough to be treated in the community.

 

“NHS Lothian services are busy but coping and I would like to pay tribute to NHS staff who are coping extremely well with this situation.

 

“It remains the case that the risk to the general public remains low but anyone with concerns should contact their GP or NHS 24’s dedicated hotline on 0800 0858 531.

 

“I want to stress that this bacteria is not passed on person to person or by drinking water.

 

“Investigations into the source of this outbreak, which are primarily led by the City of Edinburgh Council and the Health and Safety Executive and supported by Health Protection Scotland, are making good progress. I would hope that over the next few days this investigation will start to deliver answers about where the source of the outbreak might be. However, it is important to note that sometimes it is not possible to conclusively identify a source.

 

»» Read More

The Legionella Outbreak in South West Edinburgh

Legionella Bacteria - Photo Credit CDC PHIL

 

# 6370

 

There’s a rapidly spreading outbreak of Legionella in Scotland this week,  and I’ve details from the NHS and HSE. 

 

But first . . . a little background and history.

 

In July of 1976, while many of us in the health care field were waiting for the expected arrival of a swine flu pandemic (see Deja Flu, All Over Again), another medical crisis was brewing  at the Bellevue Stratford Hotel in Philadelphia.

 

This was the scene of the gathering of hundreds of veterans belonging to the American Legion, celebrating this country’s bicentennial.  Within a couple of days of their arrival, scores fell ill with a serious flu-like illness.

 

At first, many believed this was the first arrival of the expected flu pandemic, but soon it became evident that this was something else entirely.  But exactly what it was would take months to determine.

 

During this outbreak, 221 people were treated and 34 died.

 

But it wouldn’t be until early in 1977 that a definitive cause would be isolated by the CDC – a Gram negative, aerobic bacteria found growing in the hotel’s air-conditioning cooling tower – that provoked a serious form of pneumonia.

 

Dubbed `Legionnaire's Disease’ by the press, this bacterium was named Legionella, and the pneumonia it produces Legionellosis.

 

While `discovered’ in 1976 and identified the following year, Legionella had been with us, and causing serious illness, for a long time. It had caused earlier outbreaks, including one in Austin, Minnesota in 1957 (Osterholm et al., 1983) and at Saint Elizabeth’s Hospital in Washington, D.C. in 1965.  

 

The cause of these outbreaks wasn’t identified, however, until retrospective studies were conducted after the Philadelphia outbreak.  

 

We now know Legionella to be a major cause of infectious pneumonia, and that it sometimes sparks large outbreaks of illness.  According to the CDC between 8,000 and 18,000 Americans are hospitalized with Legionnaire's Disease each year, although the actual number of infected is likely higher.

 

All of which serves as prelude to the following report on the rising number of Legionella cases being diagnosed this week in Edinburgh Scotland.

 

As of today, the Associated Press is reporting 51 confirmed cases (link), one death, and more cases are expected to turn up.

 

So far, the source of this environmental pneumonia has not been identified.

 

 

Running point in the investigation is NHS Lothian, which is the public health authority for the Edinburgh area. 

 

The first press release on this outbreak came 4 days ago with the announcement of the first four cases. The next day there were six,  and the day after that . . . thirteen. 

 

Now the number stands at 51, and at least 10 more suspected cases are being tested.

 

You can read the progression of daily reports by the NHS at the link below, with the last update from yesterday.

 

Outbreak of Legionella in South West Edinburgh - Last updated 07/06/2012 AM

Update - 07/06/2012 AM

The Cabinet Secretary for Health & Wellbeing made a statement on the Legionella Outbreak at the Scottish Parliament this morning. You can watch it online at 

http://www.scottish.parliament.uk/newsandmediacentre/30912.aspx

---

Update - 06/06/2012

Resilience team report on outbreak latest

The latest reports from the Scottish Government Resilience Room (SGoRR) on the Edinburgh Legionnaires’ outbreak show that there are now 21 confirmed cases and 19 suspected cases.

 

One of the confirmed cases has died, two have been discharged from hospital and 12 are being treated in intensive care.

 

An emergency information leaflet will be delivered to all homes and businesses in affected areas tomorrow. GPs have also been provided with information on spotting the signs of infection.

 

A dedicated NHS helpline has been set up for anyone concerned and can be reached on 0800 0858 531.

 

Health Secretary Nicola Sturgeon said:

 

“The fact remains that the risk to the general public is low – however, due to the incubation period of the infection we are still expecting to see an increase in cases over the next couple of days.

(Continue . . . )

 

 

Obviously these numbers continue to rise, and press reports now differ from the numbers posted above.

 

The NHS maintains the following  website with more information on Legionella:

 

Legionnaires' disease

Introduction

Legionnaires’ disease is a potentially fatal lung infection (pneumonia) that is caused by the legionella bacteria. Legionnaires’ disease is caught by breathing in small droplets of contaminated water. It is not contagious and cannot be spread directly from person to person.

 

Initial symptoms include a high fever and muscle pain. Once the bacteria begin to infect your lungs, you may also develop a persistent cough (see Legionnaires disease - symptoms). Prompt treatment using antibiotics is essential to reduce the risk of death. See Legionnaires’ disease - treatment for more information.

(Continue . . . )

 

 

To put this in context, the largest outbreak of Legionnaires disease in recent years in the UK occurred a decade ago, in the town center of Barrow-in-Furness, Cumbria which ultimately produced 180 known infections, and 7 deaths.

 

The following 62-page report on that outbreak is available on the HSE website:

 

Report of the public meetings into the legionella outbreak in Barrow-in-Furness, August 2002

 

While doctors struggle to treat those infected, disease detectives in Scotland are working to find the environmental source of this virulent bacteria, in order to stop the outbreak.

 

I’ll update this story when new details emerge.

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UK: 2010 Flu Vaccine Policy Debated

 

 

 

# 5182

 

 

With the UK on the cusp of what may turn into the first major flu epidemic in a decade, difficult questions are being raised about this year’s flu vaccination policies. 

 

The NHS provides free influenza vaccines to groups deemed to be at high risk from the virus, and this year that includes:

 

It is recommended you have a flu jab if you:

• are 65 or over
• are pregnant (see below)
• have a serious medical condition (see box)
• live in a residential or nursing home
• are the main carer for an elderly or disabled person whose welfare may be at risk if you fall ill
• are a healthcare or social care professional directly involved in patient care
• work with poultry (see below)

 

This is essentially a return to the pre-pandemic recommendations, based on the long standing determination that those over-65, and those with chronic health conditions, are most at risk from the influenza virus.

 

Children under the age of 5 were included (a carry over from last year’s pandemic) until The Independent Joint Committee on Vaccination and Immunisation dropped that recommendation last July.

 

Now . . .  with the HPA reporting (as of Dec. 24th) 460 people in intensive care, and 27 flu-related fatalities, this year’s vaccination policy has turned into a heated medical, scientific, and political debate.

 

The novel H1N1 virus – which since it emerged has shown a predilection for those under 65 – is once again the predominant strain of influenza in the UK (but not globally . . . go figure).

 

As a result, 89% of those in Intensive care units are under the age of 65.

 

There are now accusations being made in the media, and by some Shadow Ministers (members of Her Majesty's Loyal Opposition) that the exclusion of otherwise healthy under-5’s from the high-risk list was a cost cutting move, and ill advised.

 

It should be noted that by far, the most heavily impacted age group (based on ICU admissions) are those between the ages of 16-64 (79%).

 

Under-5’s made up about 6% of the total ICU admissions (n=26).

 

Details on how many of each group had pre-existing conditions, and would have been eligible for (or actually received) the jab, have not been made available.

 

 

Health Secretary Andrew Lansley is defending the decision, stating that their vaccination program was based based on age and risk factors and was continually under review.

 

 

This morning, a report from the BBC which includes statements by John Oxford, Professor of Virology at St Bartholomew’s and the Royal London Hospital, on our need to adapt to the changing threat from influenza.

 

 

28 December 2010 Last updated at 05:48 ET

Flu vaccine policy for children defended

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UK: NHS `Just Coped’ With Pandemic

 

 

# 4405

 

 

An interesting read this morning from This Is Nottingham concerning post-pandemic wave assessments made by a variety of practitioners and medical professionals from the Nottingham, UK region.

 

Chris Locke, chief executive of the Notts Local Medical Committee (LMC),  believes that the NHS (National Health Service) `just coped’ with the pandemic.

 

 

Had it been much more severe, he states, `many services would have collapsed under the strain’.

 

 

While this article is UK-centric, many of the difficulties discussed in this article would apply to other countries as well.

 

As bad as it was, we collectively dodged a bullet with this pandemic.  It could have been a lot worse.

 

This is a long article, an informal post-mortem if you will, on the NHS response.  An official assessment is underway, and is expected in May.

 

I’ve just reproduced the opening paragraphs.  Follow the links to read it in its entirety.

 

 

NHS 'just coped' with flu pandemic

Friday, March 05, 2010, 11:14

A LEADING doctor has revealed local health services "would have collapsed under the strain" if the swine flu pandemic had been more widespread.

 

Local NHS officials expected hospitals, phone lines and GP services to be swamped after the World Health Organisation declared a swine flu pandemic last June.

 

But the disease didn't take hold as quickly or as widely as expected.

 

Chris Locke, chief executive of the Notts Local Medical Committee (LMC), has said health services across county would not have been able to cope if the threat had fully materialised.

 

He said: "Despite several years of preparation, the NHS only just managed to cope with this pandemic.

 

"If it had turned out to be as bad as predicted, many services would have collapsed under the strain.

 

"Emergency departments, out-of-hours services, GP practices and community staff were all overstretched at certain times."

 

The LMC, which represents GPs, says the Government made mistakes in the way it responded to the pandemic.

(Continue . . . )

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