# 3728
This weekend has brought a fair bit of good news about the US production of the novel H1N1 `swine’ flu vaccine.
First we learned (on Friday) that the NIH clinical trials on adults showed that a single unadjuvanted 15 μg shot provoked a good immune response, and now it appears that at least some vaccine will become available to the public the first week of October.
While the quantity of vaccine that will be available in three weeks is unstated, it is – at the very least – a symbolic victory. The US will have brought a pandemic vaccine to the public in 5 months rather than the 6 that was anticipated - and without having to sacrifice seasonal vaccine production.
There are challenges ahead, of course. Big ones.
Delivering the vaccine to the arms of the public over the next few months will involve thousands of local health departments and tens of thousands of distribution points and will require immense logistical and planning support.
And although this vaccine comes into play just 5 months after the virus was discovered, it remains to be seen how much of an impact it will have on this fall’s spread of pandemic flu.
There are also public relations challenges ahead as well.
The last time we attempted a vaccination program of this scale it bogged down and was finally abandoned due to bad publicity over the vaccine’s side effects.
While serious side effects from this unadjuvanted vaccine are unlikely (it is essential the same as the seasonal flu vaccine, only the strain has been changed), people and the press are going to be particularly alert to any reports of possible adverse reactions after the 1976 swine flu debacle.
Even if no causal link to the vaccine is apparent.
But today the news is good. Bloomberg reports on the early arrival of the H1N1 vaccine.
Swine Flu Shots to Start in Three Weeks as U.S. Cases Spread
By Tom Randall and Jason Gale
Sept. 13 (Bloomberg) -- Swine flu vaccinations may begin in three weeks, earlier than previously anticipated, after the first U.S. tests found a single shot to be effective in eight to 10 days, U.S. health officials said.
The first shots may be available by the end of this month and administered to patients the first week of October, said Nancy Cox, director of the flu division at the U.S. Centers for Disease Control and Prevention in Atlanta. Health officials had previously planned for vaccinations to begin in mid-October, requiring two shots administered three weeks apart.
Swine flu outbreaks have rippled across U.S. schools and universities after pupils returned to classes in the past few weeks. Washington State University reported more than 2,500 cases, and the CDC last week reported a nationwide spike of influenza cases months earlier than the past three flu seasons. The test results are boosting hopes the vaccine may be available in time to curb the first pandemic in 41 years, Cox said.
Related Post:
- mBio: Taubenberger et al. On the 1918 Spanish Flu
- PNAS: Virulence & Transmissibility Of H1N2 Influenza Virus In Ferrets
- Study: Kids, Underlying Conditions, And The 2009 Pandemic Flu
- EID Journal: Flu In Healthy-Looking Pigs
- Lancet: Estimating Global 2009 Pandemic Mortality
- PNAS: H1N1 Vaccination Produced Antibodies Against Multiple Flu Strains
- Indian Government Responds To Concerns Over H1N1
- Indian Expert: `Nothing Scary About Outbreak’
- NEJM: Oseltamivir Resistant H1N1 in Australia
- CIDRAP News: Signs Of Tamiflu Resistant H1N1 Spreading
- Study: Kids, Pandemic H1N1 & MRSA Co-Infection
- An Influenza Double Whammy
- WHO: Call It A(H1N1)pdm09
- JAMA: H1N1, ECMO, and Survivability
- PLoS One: Viremia In The 2009 H1N1 Pandemic Influenza
- When Pig Viruses Fly
- mBio: Lethal Synergism of H1N1 Pandemic Influenza & Bacterial Pneumonia
- Study: Reassorted H1N1-H5N1 Produced Virulent Strain
- ECDC: Risk Assessment On Australia’s Antiviral Resistant H1N1 Cluster
- Professor Peter Doherty On Bird Flu
- Australia Reports Cluster Of Antiviral Resistant H1N1
- PNAS: Reassortment Potential Of Avian H9N2
- Webinar: pH1N1 – H3N2 A Novel Influenza Reassortment
- Eurosurveillance: A `Mildly’ Resistant Strain of H1N1 Emerges
- PLoS One: H1N1 Seroprevalence Study
- Anticipating The Flu Season Down Under
- ACP Calls For Health Care Worker Immunizations
- Branswell On Flu Vaccine Matches
- Flu Vaccine Still Available, But Spot Shortages Exist
- Study: Self-Administered Vaccines In Adults
- Egypt: A Paltry Poultry Vaccine
- Lancet: Low Flu Vaccine Effectiveness
- Hong Kong: H5N1 Vaccine Recommended For Certain Lab Workers
- AAP Endorses SAGE Recommendations Keeping Thimerosal In Vaccines
- NIVW 2012
- Study Supports Safety Of Tdap Vaccine In Older Patients
- JAMA: Waning Pertussis Vaccine Effectiveness Over Time
- Revisiting The Numbers Racket
- Of Pregnancy, Flu & Autism
- Canada & Switzerland Clear Novartis Flu Vaccine For Use
- CMAJ On Mandatory Flu Shot For HCWs
- Novartis Fluad And Agriflu Vaccines Suspended In Canada
- The UK’s Whooping Cough Outbreak
- Peter Sandman On the CCIVI Vaccine Report
- CIDRAP: The Need For `Game Changing’ Flu Vaccines
- Rhode Island Adopts New Flu Vaccination Requirements For HCPs
- Vietnam Reports Progress On New Bird Flu Vaccine
- WHO: Southern Hemisphere 2013 Flu Vaccine Composition
- NPM12: Giving Preparedness A Shot In The Arm
- Yes, We Have No Pandemic . . .
- CIDRAP News Coverage Of The H5N1 NIH Workshop
- NIAID Video: How Influenza Pandemics Occur
- NEJM: Adult-Onset Immunodeficiency in Thailand and Taiwan
- NIH: News From The Human Microbiome Project
- NIAID Video: Antigenic Drift
- NIH Video: Dual Use Research Of Concern (DURC)
- U.S. Issues New DURC Oversight Rules
- How Parrot Fever Changed Public Health In America
- NIH: Investigating A Potential Treatment For Hendra & Nipah Viruses
- NIH: Any Combo Of Prime-Boost Flu Vaccine Protects Toddlers
- NIH: School Closings Effective In 2009 Pandemic
- Home Is Where The (fatal) Heart Attack Is
- NIH: Commentary On Universal Flu Vaccines
- Morens and Taubenberger: A New Look At The Panzootic Of 1872
- Morens, Taubenberger & Fauci: What’s Next For H1N1
- Study: MLV Found In CFS Patients
- NIH: Phase I Trials Of A Dengue Vaccine
- NIH: Progress Towards A Universal Flu Vaccine
- NIH: Antibodies That Work Against HIV
- NIH: Rapid Development Of Antiviral Resistance In Two Cases
- NIAID Scientists Propose New Explanation for Flu Virus Antigenic Drift
- Study: Fitness Of Novel H1N1 In Ferrets
Widget by [ Iptek-4u ]